Why Choose Charisma for Your Polynucleotides Treatment in Dubai & Abu Dhabi?
Every Polynucleotides treatment at Charisma begins with a personalized doctor consultation, advanced skin analysis, and a scientific OligoScan Test — evaluating the internal biological factors that inform your treatment plan before any injection takes place.
Our clinics are equipped with an advanced technological ecosystem, including Morpheus, Ultherapy, Fotona, PICO, HALO, and BBL HERO, often combined with leading-brand aesthetic treatments to refine your natural features. Every procedure is led strictly by internationally trained, licensed doctors with between 5 and 25+ years of clinical expertise, in premier, state-of-the-art clinical environments across Dubai’s leading hubs — trusted by a growing base of patients across the region.
What Are Polynucleotides (PN)?
Polynucleotides are chains of nucleotide monomers — each made up of a nitrogenous base (adenine, thymine, cytosine, guanine, or uracil), a sugar molecule (ribose or deoxyribose), and phosphate groups — that form the vital backbone of DNA and RNA.
In aesthetic medicine, natural DNA fragments, typically derived from salmon or trout, are used to promote skin regeneration, stimulate collagen production, and improve tissue elasticity from within.
Benefits of Polynucleotides Treatment for Skin Rejuvenation
- Improved texture & firmness — enhances collagen and elastin production, reducing the appearance of fine lines and wrinkles
- Deep hydration — polynucleotide molecules actively draw in water, giving skin a fuller, more moisturized look
- Anti-inflammatory support — helps calm redness, swelling, and irritation, making it suitable for sensitive skin
- Tissue repair — supports wound healing and cell repair, helping to improve the appearance of acne scars and stretch marks
- Antioxidant protection — helps shield skin cells from environmental stressors like UV exposure and pollution
- Natural & convenient — biocompatible salmon-derived DNA fragments offer long-lasting results with little to no recovery time
What Is Polynucleotide Treatment (PDRN Therapy)?
Polynucleotide treatment, also known as PDRN therapy (polydeoxyribonucleotide), involves injecting natural DNA fragments into the skin to harness their regenerative properties, amplifying the skin’s own natural healing and renewal processes.
How Do Polynucleotide Injections Work for Skin Rejuvenation?
Once injected, polynucleotides stimulate fibroblasts — the cells responsible for producing collagen and elastin — encouraging them to become more active. Over time, this increases skin density and thickness, improving both the structure and quality of the treated area from the inside out.
The Polynucleotide Treatment Procedure at Our Clinic
Your session begins with a consultation where our skincare professionals assess your skin health and align the treatment with your aesthetic goals. The area is then cleansed and a local anesthetic is applied for comfort.
Natural DNA fragments are administered under sterile conditions, spread uniformly across the treatment area to ensure even coverage. Your specialist adjusts the injection depth to target specific concerns, whether that’s fine lines or deeper tissue scarring. Most sessions take just 20 to 30 minutes.
Polynucleotides Treatment Aftercare Guidelines for a Smooth Recovery
Avoid direct sun exposure for 1–2 weeks after treatment and apply a broad-spectrum sunscreen (SPF 30 or above) to prevent irritation. Stick to mild, non-irritating skincare products, and avoid active ingredients like retinoids, acids, or exfoliants for the first week.
Heat and sweat can worsen redness and swelling, so avoid strenuous activity, saunas, and steam rooms for 24–48 hours. Drink plenty of water, and apply a cold compress intermittently if needed to soothe any swelling or redness.
How to Prepare Your Skin Before a Polynucleotide Injection Session
In the days leading up to your appointment, avoid active ingredients such as retinoids or exfoliants, and limit excessive sun exposure. This helps minimize skin sensitivity, ensuring your skin is in optimal condition to receive injections safely.
Who Is the Ideal Candidate for Polynucleotide (Salmon DNA) Therapy?
Polynucleotide therapy is highly recommended for individuals with aging or damaged skin, fine lines, wrinkles, or acne scars and stretch marks. Thanks to its natural anti-inflammatory properties, it’s also considered a safe and effective option for those with sensitive skin, rosacea, or active acne.
Polynucleotides Treatment Cost in Dubai & Abu Dhabi, UAE
Polynucleotide treatment at Charisma starts from AED 490 per 1ml. Final pricing is calculated during a free consultation, based on your target areas and the volume of product required.
Polynucleotides Treatment Before and After Results
Because results depend on your skin condition and the areas treated, your doctor will walk you through realistic before-and-after examples relevant to your goals during your consultation.
Polynucleotides Treatment: Frequently Asked Questions (FAQs)
Is Polynucleotide treatment painful?
The treatment is only mildly uncomfortable. A topical numbing cream is applied beforehand to keep the experience comfortable throughout.
How many sessions will I need?
Most patients benefit from a course of sessions, spaced a few weeks apart, though your doctor will recommend a plan tailored to your skin’s condition and goals.
Is Polynucleotide treatment safe?
Yes — because it uses biocompatible, salmon-derived DNA fragments, adverse reactions are rare, and the treatment is well tolerated even by those with sensitive skin.